ZIMHI™ is an opioid antagonist indicated for the emergency treatment of known or suspected opioid overdose, including fentanyl poisoning, as manifested by respiratory and/or central nervous system depression in adult and pediatric patients. ZIMHI™ is intended for immediate administration as emergency therapy in settings where opioids may be present. ZIMHI™ offers the highest dose of naloxone available as an intramuscular injection (5 mg/0.5 mL naloxone hydrochloride solution), and is packaged in a single-dose, pre-filled syringe. It is available by prescription.